Posts tagged ‘technology’
We’re all walking around with at least six billion pieces of information in our personal genome that, as the field of personalized medicine grows, can provide valuable clues to future health. When paired with clinical data from the electronic medical record (EMR), physicians will be able to provide individualized, precision medical care. The potential implications for improved health and efficiency of health care delivery are huge. So too are the technology needs to support that future.
In the not too distant future, every patient seen by providers at Penn State Milton S. Hershey Center will be offered genome analysis, something the organization’s founders could have never conceived of 50 years ago when the first shovel was plunged into the farm fields on Feb. 26, 1966, of what would become Penn State Hershey Medical Center and Penn State College of Medicine. The groundbreaking was a short three years after a $50 million gift offer from the M.S. Hershey Foundation to Penn State to establish a medical school and teaching hospital in Hershey.
“This is the most exciting time to be in medicine in terms of research capabilities and outcome for patients,” said Dr. James Broach, director of Penn State Hershey Institute for Personalized Medicine. “The first genome sequence was generated in 2003 and that took 10 years and $3 billion. Now, in one day for about $1,000, we can do the same thing.”
Every day, researchers at Penn State College of Medicine work to discover new ways to improve human health and well-being. Through technology transfer—the process of commercializing those discoveries—people across the country and the world gain access to innovative drugs, medical devices, and therapeutics.
“Physician-scientists often gain their insights and inspiration from the patients they see,” says Daniel Notterman, M.D., vice dean for research and graduate studies at the College of Medicine, professor of pediatrics, biochemistry, and molecular biology, and associate vice president for health sciences research, Penn State. “There are often several motivations, and large among those is a desire to improve the care of people who have the condition that they’re studying.”
Technology transfer is a significant part of the research process because it brings patented ideas into the marketplace.
“If we were only able to conduct and present research in the form of scientific papers or presentations at conferences, that wouldn’t result in a product [because] the information becomes public,” says Keith Marmer, D.P.T., M.B.A., associate dean for research innovation and director of the Office of Technology Development. “Drug companies are typically not going to want to invest in excess of $1 billion to try to bring a drug to market if it is based on publicly available information as there is no competitive advantage to do so.”
In practice, it requires several players to make the commercialization of a scientific discovery successful. Each stakeholder, such as academics, venture capital investors, and economic development groups, helps make up a so-called “entrepreneurial ecosystem” in a particular geographic area. “[The ecosystem] also includes professional service organizations, such as the accounting firms and law firms that help support the entrepreneurial activity in the region,” Marmer says.
With more than $100 million in research taking place at the college every year, the institution’s vision is to serve as a leader and a catalyst for biomedical innovations in central Pennsylvania. “We want to be able to drive that research out into that entrepreneurial ecosystem but be fully engaged with all the ecosystem partners,” he says. “We also aim to be recognized as a leader nationally and globally.” (more…)
Bioanalyzer 2100. Nanodrop ND1000. BeadXpress. SpectraMax 2. Denator Stabilizor.
No, these aren’t weapons from an episode of Star Trek–they’re a sampling of the sophisticated equipment in the Functional Genomics Core Facility at Penn State College of Medicine.
Under Assistant Professor of Pharmacology and Director Willard Freeman, Ph.D., the facility has become one of the nation’s leading resources for the study of molecular biology. The facility’s mission is to better understand disease mechanisms and enable diagnosis at earlier and more preventable stages. The facility itself is a prime example of how medicine has evolved from a “treat and wait” approach towards personalized medicine. While most of the nation’s leading educational medical centers have similar facilities, Penn State’s facility has developed a reputation for being at the forefront of exploration into this relatively uncharted medical landscape.