Posts tagged ‘research’
For researchers early in their careers, it’s not just funding that matters—mentorship is also critical for success.
Dr. Dan Morgan has been studying cannabinoid signaling in the brain. Dr. Greg Lewis recently developed simulation software for fracture surgeries. Dr. Joslyn Kirby investigated bundled payments for management of a skin condition. These three Penn State College of Medicine doctors received guidance from senior researchers, along with $200,000 to fund their research, through the College’s Junior Faculty Research Scholar Awards program.
The program, launched in 2011, provides support to early-stage investigators in basic, clinical, and translational science research.
“It’s a way for us to jump start the research programs and career development of researchers here,” says program co-director Dr. Sarah Bronson, who is also director of Research Development and Interdisciplinary Research and co-director of the Junior Faculty Development Program. “We put equal weight on funding the scholar’s research program and recognizing a career and development plan that is going to make that research program happen.”
To that end, applicants don’t just propose the research they want to do. They also submit mentorship “dream team”—at least three experienced investigators who will provide advice and assistance in developing and executing a research proposal and a career development plan. The mentoring team meets with the scholar a minimum of once every six months.
Each scholar’s award is named to honor the contributions of senior investigators at Penn State Hershey who made a difference through their own research and through the mentoring of colleagues and trainees.
A new printing technology at Penn State Hershey gives doctors and researchers new possibilities.
Instead of ink on paper, a 3D printer can “print” strands of material in layers to create solid items. Doctors can imagine, design and create prototypes of everything from surgical tools to medical devices like abdominal drains and orthopedic screws.
“There is a big splash about 3D printing — and with good reason,” said Dr. Randy Haluck, vice chairman for technology and innovation for the Department of Surgery.
In the past, a doctor who wanted only a few of something for testing or custom use would have to go through a manufacturing process set up to make thousands of the same thing. Now, a single item or a small batch can be printed.
“This is faster, more efficient and cheaper,” said Dr. Peter Dillon, chair, Department of Surgery.
Just as a draft of text can be printed on a two-dimensional surface and then tweaked and revised before printing again, the same can be done with the 3D machine.
With a career in retrovirology research, a passion for education, and a 24-year history at Penn State Hershey, Dr. Leslie Parent brings a strong skillset to her new position as vice dean for research and graduate education.
Parent transitioned to the role in early June from her former position as chief of the Division of Infectious Disease.
“I thought it was a great opportunity to help other people do better research,” Parent said. “That was what really motivated me: the opportunity to enhance the research going on here at the College of Medicine. We already have excellent, successful investigators. We can take something that already has such a strong foundation and look for ways to promote our research, engage more people in our research, and build a better and more complete infrastructure for research.”
Parent started in the Division of Infectious Disease as a fellow, completed a post-doctoral fellowship in retrovirology, and started her own NIH-funded laboratory in 1998. She was named chief of the division in 2007 and was later asked to co-lead the college’s M.D./Ph.D. program, helping train future physician scientists.
Parent believes she brings an optimistic attitude and persistence to the role.
“I like to explore all the possibilities and do our best to achieve the things we set out to do,” she said. “I like to set goals and then gather people around to work as a team to achieve those objectives. I think team work is really important and I hope that I can be someone who can build teams and use a lot of different people’s talents to achieve the things we want to do here.”
An engineer, a surgeon, and a machinist walk into a conference room.
It might sound like the start of a bad joke, but it’s a regular scene in Penn State Hershey’s Division of Artificial Organs, where experts in vastly different fields bring their knowledge together to design, manufacture, implant and test artificial hearts in one location.
Cardio-thoracic surgeon Dr. William S. Pierce formed the team in 1970 when he came to Penn State’s then-new Milton S. Hershey Medical Center after working on artificial heart development for the National Institutes for Health. Penn State’s strong engineering staff and Hershey’s suburban location offered the resources to develop the kind of collaborative program he envisioned.
Forty-five years later, Dr. Gerson Rosenberg, chief of the Division of Artificial Organs, can walk down the hall from his office to a machine shop, plastics lab, metal-polishing station and rooms where mock circulatory testing is done on heart-assist devices for adults and children. An assist device helps a sick heart do its work so it can rest while the patient awaits a transplant, so researchers are always looking for ways to improve the devices to work better and for longer.
At a nearby facility, veterinarians provide pre- and post-op care for animals implanted with pediatric heart-assist devices and a new pneumatic heart pump — operated by air pressure — that could improve the lives of young adults and adolescents born with congenital heart defects.
“We are unique in that everything from start to finish is done in one location,” Rosenberg said. (more…)
Dr. Neal Thomas has made research his life’s work.
The newly named associate dean for clinical research hopes to help Penn State Hershey’s clinical research mission grow. One reason he is vested in seeing the expansion of clinical research is because he was personally affected by it — twice.
“In 2002, my youngest son was born premature and was given a medicine called surfactant into his lungs to combat lung disease that can happen from prematurity,” Thomas, a professor of pediatrics and public health sciences, said.
Being a researcher involved with surfactant use in older children, and also studying the surfactant genes and their impact on young children with lung disease, he was aware of the early clinical trial literature treating premature lungs. The fact that his son benefited from that early work would strengthen Thomas’s research interest in surfactant for years to come.
“It probably saved his life, but it certainly affected his lungs so that he is completely healthy now,” Thomas said. ”That wouldn’t have happened if scientists and physicians hadn’t conducted the clinical research to get to that point.”
He personally benefited from clinical research last year after having a heart attack.
In 1977 the U.S. Food and Drug Administration banned women “of child-bearing potential” from participating in clinical trials. This was in part due to thousands of children worldwide being born with missing and malformed limbs after their mothers had taken thalidomide — often prescribed in the 1950s for nausea and as a sleep aid.
A decade and a half later, in 1993, the FDA lifted this ban after Congress passed the National Institutes of Health Revitalization Act. However, as Alina Salganicoff noted in her keynote address at Penn State’s 2015 Women’s Health Research Day on April 28, women are still poorly represented in research and clinical trials.
Women’s Health Research Day was held at the Penn State College of Medicine campus for the second year in a row and researchers from both the Hershey and University Park campuses attended. Due to the number of applications this year, two more research presentation slots and 11 more poster presentations were added.
Poster presentations featured the work of faculty members, residents, graduate students and medical students. The researchers’ fields of expertise ranged from obstetrics and gynecology to kinesiology to public health sciences, and seemingly everywhere in between, covering a vast array of women’s health topics.
As part of an initiative to educate students in the surrounding areas about research related to health, faculty members from Penn State College of Medicine, in conjunction with colleagues from Penn State Harrisburg, Juniata College, and the Raystown Field Station offered 16 sophomores from Susquehanna Township High School and five of their teachers a week-long, summer opportunity to take a closer look at environmental and medical research techniques, and the interchange between the two areas of science. The formal title of the program is SEPA-CREST, so named for the Science Education Partnership Award (SEPA) that funded it and the opportunity it provided for Collaborative Research Experiences for Students and Teachers (CREST). It serves not only as a vehicle for students and teachers to gain more intensive experience in science, but also as a research opportunity for college faculty to gauge their ability to improve science literacy with these groups.
Participants travelled to the Raystown Field Station, an environmental center in Huntingdon, PA operated by Juniata College for a multidisciplinary study of the interactions between humans and the environment.
“The great thing about a week-long experience like this is that we’ve been able to address a wide range of topics and techniques,” said Sarah Bronson, Ph.D., associate professor of cellular and molecular physiology, Penn State College of Medicine. “Each of the students are drawn to different areas in science, so this approach raises the likelihood that we’ll score a hit with one of the 16 kids and they think, ‘I want to know more about that’ or ‘I’d like to do that when I grow up.’” (more…)